- Specifically, the LOD increases rapidly when the serum amount is below 0.5 g, as exemplified with 2,2′,4,4′-terabromodiphenyl ether (PBDE-47) in Figure 1. Due to this observation, the detection frequency, by analyte, for samples having a serum amount of 5 g was compared to the overall detection frequency (Supporting Information, Table S1).
- The present study was conducted to compare the tissue disposition of a polybrominated compound, 2, 2', 4, 4', 5- pentabromodiphenyl ether (BDE 99) in tadpole and juvenile stages of Xenopus tropicalis (West African clawed frog).
- 2,4-dibromophenyl 2,3,4-tribromophenyl ether is a polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 3, 4, 2', and 4' positions have been replaced by bromines.
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IRIS Toxicological Review of Pentabromodiphenyl Ether (Final Report)
Contact
Master Of Typing 2 4 4 5 Pentabromodiphenyl Ethernet Cable
phone: (202) 566-1676
email: [email protected]
. Pubblication: 'Ice photolysis of 2,2',4,4',6-pentabromodiphenyl ether (BDE-47): Laboratory investigations using solid phase microextraction' Analytica Chimica Acta, 2008. Environmental Impact Assessment of liquid wastes of promace factory'.
Citation:
Ocr butler 1 2 1download mac os x. U.S. EPA. IRIS Toxicological Review of Pentabromodiphenyl Ether (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-07/006F, 2008.
Impact/Purpose:
The draft assessments will present reference values for the noncancer effects (RfD and RfC) and a cancer assessment, where supported by available data, for the BDE-47, BDE-99, BDE-153, and BDE-209 congeners of polybrominated diphenyl ethers.
Description:
The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to 2,2',4,4',5-pentabromodiphenyl ether. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of 2,2',4,4',5-pentabromodiphenyl ether (BDE-99).
The majority of the available toxicological information on the pentabromodiphenyl ether homolog group (CAS No. 32534-81-9) relates to the pentabromodiphenyl congener BDE-99 (CASRN 60348-60-9). Toxicological information related to other congeners in the pentabromodiphenyl ether homolog group is also discussed. However, this health assessment does not deal with commercial mixtures of brominated diphenyl ether homologs containing pentabromodiphenyl ether as one of the constituents of commercial formulations. In addition to BDE-99, IRIS health assessments have also been prepared for three other polybrominated diphenyl ether congeners: tetraBDE-47, hexaBDE-153, and decaBDE-209. These four congeners are those for which toxicological studies suitable for dose-response assessments were available and are the ones most commonly found in the environment and human biological media.
URLs/Downloads:
U. S. EPA. Toxicological Review of 2,2',4,4',5-pentabromodiphenyl Ether (Final Report). ORD, NCEA, Washington, DC. EPA/635/R-07/006F, 2008 (PDF,128 pp, 1405 KB, about PDF)Record Details:
Record Type: DOCUMENT (IRIS ASSESSMENT)Record Last Revised: 12/08/2011
Record ID: 190309
Kulkarni, Pushkar, 2005.Polyhalogenated organic pollutants in amphibians. Second cycle, A1N, A1F or AXX ( AXX). Uppsala: SLU, Dept. of Biomedical Sciences and Veterinary Public Health
PDF 1MB |
Abstract
Master Of Typing 2 4 4 5 Pentabromodiphenyl Ethereal
Polyhalogenated organic pollutants are xenobiotics, which are believed to cause considerable environmental pollution and human health problems as a result of their persistence, toxicity, and transformation into hazardous metabolites. These chemicals are persistent and are biomagnificated in the ecosystem. Axure rp pro 7 0 0 3189 download free. Amphibians (frogs) are considered as reliable indicators of environmental health because they form an important link in the food chain between insects and vertebrates. Furthermore, they are inhabitants of both
aquatic and terrestrial environments and occupy different positions in the food web at different stages of their life cycle. Download pdf protector 1 3 crack. The different stages in the life cycle of frogs are tadpole, juvenile and adult stages.
aquatic and terrestrial environments and occupy different positions in the food web at different stages of their life cycle. Download pdf protector 1 3 crack. The different stages in the life cycle of frogs are tadpole, juvenile and adult stages.
The tadpole is transformed to a juvenile frog by metamorphosis. Disruption of this life cycle by xenobiotics can have disastrous effects on the amphibian populations. Polyhalogenated organic compounds have been known to cause endocrine disruption, effects on gene expression and induction of cytochrome P 450 enzymes in frogs. The present study was conducted to compare the tissue disposition of a polybrominated compound, 2, 2', 4, 4', 5-
pentabromodiphenyl ether (BDE 99) in tadpole and juvenile stages of Xenopus tropicalis (West African clawed frog). The study was performed using whole-body autoradiography and scintillation counting at different time intervals after dietary exposures of 14CBDE 99 at stage 54 (tadpoles) and stage 66 (juvenile frogs). From the results of the study it was concluded that there was a significant
difference between the uptake and retention of the chemical between tadpoles and frogs. Juvenile frogs had higher uptake and retention of the radio labelled chemical than tadpoles. The substance was retained in adipose tissue over 64 days in both stages. However, the localisation of substance was similar in both stages.
pentabromodiphenyl ether (BDE 99) in tadpole and juvenile stages of Xenopus tropicalis (West African clawed frog). The study was performed using whole-body autoradiography and scintillation counting at different time intervals after dietary exposures of 14CBDE 99 at stage 54 (tadpoles) and stage 66 (juvenile frogs). From the results of the study it was concluded that there was a significant
difference between the uptake and retention of the chemical between tadpoles and frogs. Juvenile frogs had higher uptake and retention of the radio labelled chemical than tadpoles. The substance was retained in adipose tissue over 64 days in both stages. However, the localisation of substance was similar in both stages.
Master Of Typing 2 4 4 5 Pentabromodiphenyl Ethernet
Main title: | Polyhalogenated organic pollutants in amphibians |
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Authors: | Kulkarni, Pushkar |
Supervisor: | UNSPECIFIED |
Examiner: | UNSPECIFIED |
Series: | Report/International Master of Science Programme, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences |
Volume/Sequential designation: | 51 |
Year of Publication: | 2005 |
Level and depth descriptor: | Second cycle, A1N, A1F or AXX |
Student's programme affiliation: | MSCVE Master of Science Programme in Veterinary Medicine 90 HEC |
Supervising department: | (VH) > Dept. of Biomedical Sciences and Veterinary Public Health |
Keywords: | 2, 2', 4, 4', 5-pentabromodiphenyl ether, BDE 99, PBDE, tissue disposition, frogs, Xenopus tropicalis, polyhalogenated organic pollutants |
URN:NBN: | urn:nbn:se:slu:epsilon-s-764 |
Permanent URL: | http://urn.kb.se/resolve?urn=urn:nbn:se:slu:epsilon-s-764 |
Subjects: | Animal ecology Animal diseases |
Language: | English |
Additional Information: | Överförd från avhandlingsarkivet/Transferred from the Dissertations and Graduate Thesis Archive |
Deposited On: | 21 Nov 2011 10:50 |
Metadata Last Modified: | 20 Apr 2012 14:23 |
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